Overview

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins produced by many cell types throughout development (Gurdon et al.). It is a disulfide-linked homodimer (two beta-A chains) that binds to heteromeric complexes of a type I (Act RI-A and Act RI-B) and a type II (Act RII-A and Act RII-B) serine-threonine kinase receptor (Attisano et al.). Activins primarily signal through SMAD2/3 proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (McDowell et al.). Activin A maintains the undifferentiated state of human embryonic stem cells (James et al.; Xiao et al.) and also facilitates differentiation of human embryonic stem cells into definitive endoderm (D’Amour et al.).

Alternative Names:

Activin beta-A chain, EDF, Erythroid differentiation protein, FRP, FSH-releasing protein, INHBA, Inhibin beta-A chain, Inhibin beta-1

Cell Type:

Pluripotent Stem Cells; Other; Endoderm, PSC-Derived; Mesoderm, PSC-Derived

Species:

Human

Area of Interest:

Stem Cell Biology; Epithelial Cell Biology

Molecular Weight:

26.2 kDa

Purity:

≥ 95%

品牌介绍

STEMCELL

STEMCELL Technologies 成立于 1993 年,是加拿大最大的生物科技公司,为生命科学研究领域提供专业的细胞培养基和细胞分选产品。

STEMCELL Technologies Inc. is a Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research. Driven by science and a passion for quality, STEMCELL supports the advancement of scientific research around the world with our catalogue of more than 2000 cell biology research tools.

产品列表：

No.	品牌	货号	名称	规格
1	stemcell	60026	Anti-Dextran Antibody, Clone DX1	100ug
2	stemcell	60012	Anti-Human CD32 Antibody, Clone IV.3	100ug
3	stemcell	60004PE.1	Anti-Human CD14 Antibody, Clone M5E2	25tests
4	stemcell	60005AD	Anti-Human CD19 Antibody, Clone HIB19	100tests
5	stemcell	60018AD.1	Anti-Human CD45 Antibody, Clone HI30	25tests
6	stemcell	02002	Human IFN-gamma ELISA Kit	2plates
7	stemcell	02006	Human IL-2 ELISA Kit	2plates
8	stemcell	02012	Human IL-10 ELISA Kit	2plates
9	stemcell	02020	Mouse IFN-gamma ELISA Kit	2plates
10	stemcell	02030	Mouse TNF-alpha ELISA Kit	2plates
11	stemcell	01630	Erythropoietin (EPO) ELISA Kit	1kit
12	stemcell	27000	STEMgrid™-6	1grid
13	stemcell	27270	Reversible Strainers	25/box
14	stemcell	27100	35 mm Culture Dishes	10dishes
15	stemcell	20125	RoboSep™Filter Tips	8racks