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主营:细胞治疗中枢神经系统和肝脏疾病的研究
℡ 4000-520-616
℡ 4000-520-616
Stemcell/Human Recombinant BDNF, ACF/10 u00b5g/78133
产品编号:78133
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Stemcell
公      司:Stemcellsinc,inc
公司分类:
Stemcell/Human Recombinant BDNF, ACF/10 u00b5g/78133
商品介绍

Overview

Brain-derived neurotrophic factor (BDNF), like nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4), is a member of the NGF family of neurotrophins, which are required for the differentiation and survival of specific neuronal subpopulations in both the central and the peripheral nervous systems (Minichiello & Klein; Minichiello et al.). BDNF binds with high affinity to the TRKB kinase receptor, and activates AKT and ERK pathways (Mattson et al.). It is expressed in hippocampus, cortex, and synapses of the basal forebrain. BDNF acts as a survival factor for human embryonic stem cells when plated on either feeder cells or Corning® Matrigel® (Pyle et al.). BDNF regulates synaptic transmission and plasticity at adult synapses in the central nervous system, contributes to adaptive neuronal responses including long-term potentiation, long-term depression, certain forms of short-term synaptic plasticity, as well as homeostatic regulation of neuronal excitability (Reichardt). It also has a role in neurogenesis by promoting survival and growth of dorsal root ganglion cells, and hippocampal and cortical neurons (Binder & Scharfman). BDNF, together with glial cell-derived neurotrophic factor (GDNF) and other supplements, is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into neurons (Brafman). This product is animal component-free.
Alternative Names:
Abrineurin, ANON2, BULN2, Neurotrophin, MGC34632
Cell Type:
Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
Area of Interest:
Neuroscience; Stem Cell Biology
Molecular Weight:
13.6 kDa monomer; 27.3 kDa dimer
Purity:
≥ 95%
品牌介绍

STEMCELL


STEMCELL Technologies 成立于 1993 年,是加拿大最大的生物科技公司,为生命科学研究领域提供专业的细胞培养基和细胞分选产品。


STEMCELL Technologies Inc. is a Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research. Driven by science and a passion for quality, STEMCELL supports the advancement of scientific research around the world with our catalogue of more than 2000 cell biology research tools.


产品列表:



No.

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货号

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规格

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5

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6

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7

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Human IL-2 ELISA Kit

2plates

8

stemcell

02012

Human IL-10 ELISA Kit

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9

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Mouse IFN-gamma ELISA Kit

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10

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Mouse TNF-alpha ELISA Kit

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11

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12

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