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主营:细胞治疗中枢神经系统和肝脏疾病的研究
℡ 4000-520-616
℡ 4000-520-616
Stemcell/Anti-Human CD45RA Antibody, Clone HI100/25 u00b5g/100-0320
产品编号:100-0320
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Stemcell
公      司:Stemcellsinc,inc
公司分类:
Stemcell/Anti-Human CD45RA Antibody, Clone HI100/25 u00b5g/100-0320
商品介绍

Overview

The HI100 antibody reacts with an extracellular epitope on the CD45RA isoform of CD45, a type I transmembrane glycoprotein and member of the protein tyrosine phosphatase family (receptor class 1/6 subfamily). Alternative splicing of exons 4, 5, and 6 that encode the extracellular RA, RB, and RC polypeptides of CD45 gives rise to several isoforms with molecular masses of 180 - 240 kDa. Excision of exon 4 generates the ~220-kDa CD45RA isoform, which is expressed on naïve T cells, subsets of B cells and monocytes, and medullary thymocytes. CD45RA functions to enhance signaling through both the T cell receptor and B cell receptor. The HI100 antibody is commonly used in combination with antibodies against the CD45RO isoform to discern naïve and memory T cells and is useful for identifying the suppressor/inducer subset of CD4+ lymphocytes. The proportion of CD45RA+ T cells typically decreases with age.
Subtype:
Primary Antibodies
Target Antigen:
CD45RA
Alternative Names:
B220, CD45, GP180, Lyt-4, Ly-5, LY5, L-CA, LCA, Protein tyrosine phosphatase receptor type C, PTPRC, T200
Reactive Species:
Chimpanzee; Human
Conjugation:
APC-Cyanine7; Biotin; PE; Unconjugated
Host Species:
Mouse
Cell Type:
Granulocytes and Subsets; Hematopoietic Stem and Progenitor Cells; Leukocytes; Lymphocytes
Application:
CyTOF; ELISA; FACS; Flow Cytometry; Functional Assay; Immunoaffinity Chromatography; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Radioimmunoassay; Western Blotting
Area of Interest:
Immunology
Clone:
HI100
Gene ID:
5788
Isotype:
IgG2b, kappa
品牌介绍

STEMCELL


STEMCELL Technologies 成立于 1993 年,是加拿大最大的生物科技公司,为生命科学研究领域提供专业的细胞培养基和细胞分选产品。


STEMCELL Technologies Inc. is a Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research. Driven by science and a passion for quality, STEMCELL supports the advancement of scientific research around the world with our catalogue of more than 2000 cell biology research tools.


产品列表:



No.

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